Search hotels in Santa Cruz Region, Bolivia
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Check out these popular cities in Santa Cruz Region
Santa Cruz de la Sierra
1025 hotelsSamaipata
62 hotelsEl Pari
39 hotelsIsla del Mono
2 hotelsSantiago de Chiquitos
3 hotelsHamacas
9 hotelsVallegrande
5 hotelsVila El Carmen
5 hotelsSan Ignacio de Velasco
2 hotelsLa Playa Bejarano
42 hotels
Stay in Santa Cruz Region's best hotels!
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Cosmopolitano Hotel Boutique
Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical centre of Santa Cruz de la Sierra. Guests can enjoy the on-site bar.

TRYP by Wyndham Santa Cruz
Situated in Santa Cruz de la Sierra, 1.6 km from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz features accommodation with an outdoor swimming pool, free private parking, a...

YVY CASA HOTEL
Located in Samaipata, 10 km from Samaipata Fort, YVY CASA HOTEL provides accommodation with a garden, free private parking and a terrace.

El Pueblito Hotel Boutique
Situated in Samaipata, 11 km from Samaipata Fort, El Pueblito Hotel Boutique features accommodation with an outdoor swimming pool, free private parking, a garden and a shared lounge.

Hotel Cortez
Boasting an outdoor swimming pool, gym and spa facilities, Hotel Cortez has chic and spacious rooms in Santa Cruz de la Sierra. Free WiFi access is available.

Lido Hotel
Lido Hotel features accommodation in Santa Cruz de la Sierra near Metropolitan Cathedral and Gabriel Rene Moreno Autonomous University.

Chairu Eco Hotel
Chairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra.

Hampton by Hilton Santa Cruz
Located in Santa Cruz de la Sierra, 2.1 km from Gabriel Rene Moreno Autonomous University, Hampton by Hilton Santa Cruz provides accommodation with a fitness centre, free private parking, a garden and...

LP Equipetrol
Located in the commercial district of Equipetrol, this property offers accommodations with free WiFi access in Santa Cruz de la Sierra.

Hotel Sirari By Regina
Situated in Santa Cruz de la Sierra, 1.9 km from Gabriel Rene Moreno Autonomous University, Hotel Sirari By Regina features accommodation with an outdoor swimming pool, free private parking, a fitness...

Most booked hotels in Santa Cruz Region in the past month
Popular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.9Fabulous - What previous guests thought, 275 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.4Good - What previous guests thought, 178 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.9Fabulous - What previous guests thought, 797 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 9.0Superb - What previous guests thought, 589 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.7Fabulous - What previous guests thought, 692 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 9.1Superb - What previous guests thought, 1,106 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.3Good - What previous guests thought, 140 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.8Good - What previous guests thought, 1,105 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.0Very good - What previous guests thought, 392 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.5Very good - What previous guests thought, 187 reviews
Santa Cruz Region's best hotels with breakfast
ibis Santa Cruz de la Sierra
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.9Fabulous - What previous guests thought, 275 reviewsSet in Santa Cruz de la Sierra, 1.3 km from Arenal Park, ibis Santa Cruz de la Sierra offers accommodation with a shared lounge, free private parking, a restaurant and a bar.
From US$80 per nightNovotel Santa Cruz De La Sierra
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.5Very good - What previous guests thought, 187 reviewsSet in Santa Cruz de la Sierra, 3.5 km from Gabriel Rene Moreno Autonomous University, Novotel Santa Cruz De La Sierra offers accommodation with an outdoor swimming pool, free private parking, a...
From US$126 per nightChairu Eco Hotel
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.9Fabulous - What previous guests thought, 797 reviewsChairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra.
From US$80 per nightSwissotel Santa Cruz de La Sierra
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.9Fabulous - What previous guests thought, 278 reviewsSituated in Santa Cruz de la Sierra, 4.5 km from Gabriel Rene Moreno Autonomous University, Swissotel Santa Cruz de La Sierra features accommodation with an outdoor swimming pool, free private parking...
From US$166.50 per nightDelfines Collection Hotel by Mercure
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.0Very good - What previous guests thought, 293 reviewsLocated in Santa Cruz de la Sierra, 2.2 km from Gabriel Rene Moreno Autonomous University, Delfines Collection Hotel by Mercure provides accommodation with an outdoor swimming pool, free private...
From US$65.12 per nightHampton by Hilton Santa Cruz
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.7Fabulous - What previous guests thought, 351 reviewsLocated in Santa Cruz de la Sierra, 2.1 km from Gabriel Rene Moreno Autonomous University, Hampton by Hilton Santa Cruz provides accommodation with a fitness centre, free private parking, a garden and...
From US$104.06 per nightLP Equipetrol
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.0Very good - What previous guests thought, 391 reviewsLocated in the commercial district of Equipetrol, this property offers accommodations with free WiFi access in Santa Cruz de la Sierra.
From US$66.89 per nightHotel Sirari By Regina
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.5Very good - What previous guests thought, 234 reviewsSituated in Santa Cruz de la Sierra, 1.9 km from Gabriel Rene Moreno Autonomous University, Hotel Sirari By Regina features accommodation with an outdoor swimming pool, free private parking, a fitness...
From US$95 per night
Budget hotels in Santa Cruz Region
HOTEL OSHO
Hotel in Santa Cruz de la SierraCheap hotelScored out of 10, guest rating 8.3Very good - What previous guests thought, 644 reviewsSituated in Santa Cruz de la Sierra, 400 metres from Güembé Biocentre and Guazú Ivaga Park, HOTEL OSHO features accommodation with an outdoor swimming pool, free private parking, a fitness centre and...
From US$49.50 per nightPrince Hotel
Hotel in Santa Cruz de la SierraCheap hotelScored out of 10, guest rating 8.0Very good - What previous guests thought, 392 reviewsSet in Santa Cruz de la Sierra, within 1.9 km of Sacred Art Museum and 2.6 km of Metropolitan Cathedral, Prince Hotel offers accommodation with a garden and as well as free private parking for guests...
From US$56 per night- Scored out of 10, guest rating 8.3Very good - What previous guests thought, 316 reviews
The LP Santa Cruz Hotel is a 3-star hotel located few metres from Blacutt Square in central Santa Cruz. It offers rooms with cable TV, a minibar and free Wi-Fi.
From US$61.83 per night - Scored out of 10, guest rating 8.6Fabulous - What previous guests thought, 11 reviews
Set in Santa Cruz de la Sierra, 500 metres from Sacred Art Museum, Santa Cruz Home features a terrace and views of the city.
From US$24 per night - Scored out of 10, guest rating 8.4Very good - What previous guests thought, 15 reviews
Hotel Boutique Plaza24 has a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a shared kitchen and room service.
From US$60 per night Hotel Maywa
Hotel in Santa Cruz de la SierraCheap hotelScored out of 10, guest rating 8.8Fabulous - What previous guests thought, 87 reviewsSituated in Santa Cruz de la Sierra, 3.1 km from Güembé Biocentre and Guazú Ivaga Park, Hotel Maywa features accommodation with a fitness centre, free private parking, a shared lounge and a terrace.
From US$57 per night- Scored out of 10, guest rating 7.8Good - What previous guests thought, 1,105 reviews
Featuring an outdoor pool, La Siesta Hotel offers accommodations in Santa Cruz de la Sierra. Free WiFi access is available.
From US$83.62 per night - Scored out of 10, guest rating 6.4Pleasant - What previous guests thought, 259 reviews
Set in Santa Cruz de la Sierra, within 14 km of Arenal Park and 15 km of 24th of September Metropolitan Plaza, Hotel Viru Viru II offers accommodation with a fitness centre and free WiFi throughout...
From US$45 per night
Hotels in Santa Cruz Region that you can book without a credit card
LA CASONA Hotel Boutique
Hotel in CamiriNo credit card neededScored out of 10, guest rating 8.4Very good - What previous guests thought, 17 reviewsBoasting a terrace and barbecue facilities, LA CASONA Hotel Boutique is set in Camiri.
From US$40 per nightEx Hotel Asturias Centrico
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.3Good - What previous guests thought, 140 reviewsSituated in Santa Cruz de la Sierra, 800 metres from Sacred Art Museum, Ex Hotel Asturias Centrico features accommodation with an outdoor swimming pool, free private parking, a garden and a terrace.
From US$26.68 per nightResidencial IKANDIRE ll
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.2Good - What previous guests thought, 280 reviewsResidencial IKANDIRE ll is located in Santa Cruz de la Sierra, 1.4 km from Metropolitan Cathedral and 1.3 km from Güembé Biocentre and Guazú Ivaga Park.
From US$14 per nightHotel Arenal
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.4Good - What previous guests thought, 178 reviewsFeaturing a swimming pool, a fitness centre and a restaurant, Hotel Arenal offers rooms with free Wi-Fi and flat-screen TVs in Santa Cruz de la Sierra. Free parking is provided.
From US$69.90 per nightMansión By Hotel Casablanca
Hotel in SamaipataNo credit card neededScored out of 10, guest rating 6.5Pleasant - What previous guests thought, 6 reviewsMansión By Hotel Casablanca is a 2-star property set in Samaipata. The property is non-smoking and is situated 9.2 km from Samaipata Fort. All rooms in the hotel are fitted with a flat-screen TV.
From US$42.90 per nightHotel Casa Blanca
Hotel in La Playa BejaranoNo credit card neededHotel Casa Blanca is a 5-star property set in La Playa Bejarano. The units come with air conditioning, a flat-screen TV with satellite channels, a fridge, a coffee machine, a shower, free toiletries...
From US$33 per nightHotel Condominio Casa Blanca
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.4Good - What previous guests thought, 5 reviewsSet in Santa Cruz de la Sierra, 2 km from Gabriel Rene Moreno Autonomous University, Hotel Condominio Casa Blanca offers accommodation with a fitness centre, free private parking, a garden and a...
From US$35 per nightHotel el Marqués
Hotel in VallegrandeNo credit card neededScored out of 10, guest rating 7.7Good - What previous guests thought, 14 reviewsFeaturing a terrace, Hotel el Marqués is set in Vallegrande. Among the facilities of this property are a restaurant, room service and a 24-hour front desk, along with free WiFi throughout the property...
From US$38.50 per night
FAQs about hotels in Santa Cruz Region
See reviews by guests who stayed at hotels in Santa Cruz Region
- From US$105 per nightScored out of 10, guest rating 9.5Exceptional - What previous guests thought, 189 reviewsI am thrilled to give El Pueblito a flawless and exceptional review, rating it a perfect 10 out of 10! This remarkable accommodation has surpassed all our expectations, establishing itself as the finest place we have ever stayed in after years of extensive traveling. El Pueblito elevates the concept of relaxation to an entirely new level with its flawless service, an outstanding team of staff, delightful animals and birds, delectable cuisine, breathtakingly picturesque surroundings, and an enchanting atmosphere of tranquility. Every inch of El Pueblito's premises reflects meticulous care and remarkable craftsmanship, creating an atmosphere that is truly awe-inspiring. Prior to our visit, we had concerns about the WiFi speed, which is crucial for our work as teachers who rely on daily online classes with cameras. However, we were pleasantly surprised as everything worked flawlessly. The WiFi signal was strong enough in our room, and it was even better in the summer house (gazebo) located in the center of the square. This spot quickly became my favorite place to work, offering both power outlets and shade. Therefore, I would like to assure any fellow business travelers that the internet connection at El Pueblito is reliable 24/7. Moreover, the shower facilities were excellent, providing us with wonderfully hot water. Despite visiting in late autumn, the rooms and reception area were kept comfortably warm with the help of heaters and an abundance of cozy blankets. Notably, the nearby winery is a charming destination that should not be missed. We highly recommend booking a tour, especially considering its convenient proximity to El Pueblito. Our fond memories are incomplete without mentioning Patricia, the charming ginger cat, and the friendly dogs who added an extra layer of warmth and joy to our stay. In summary, El Pueblito has exceeded all our expectations, offering an unforgettable experience that deserves the highest praise.Guest review byAleksandrRussia
- From US$65 per nightScored out of 10, guest rating 9.0Superb - What previous guests thought, 83 reviewsThe accommodation was wonderful – from the room to the garden, everything was just perfect. The place and the hosts were exceptional. It was extraordinarily clean, and the room was full of thoughtful details. The balcony was beautiful, and the location couldn't have been better. Simply a place to feel at home and completely relaxed. On top of that, we had an extremely delicious breakfast.Guest review byNiclasAustria
- From US$153 per nightScored out of 10, guest rating 9.2Superb - What previous guests thought, 219 reviewsGreat hotel in the heart of SC, super clean, great facilities and staff. Breakfast is pretty good with basic options, great coffee. Beds and pillows are super comfortable. Definitely 5 star hotel. Interior design is interesting and sswimming pool area is very relaxing. Staff super attentive. Highly recommend to stay in SC.Guest review byAndrewCosta Rica
- From US$61.83 per nightScored out of 10, guest rating 8.3Very good - What previous guests thought, 316 reviewsBreakfast was the only thing I did not like at this hotel. I did not find the food very appealing. The cakes were not tasty and did not have enough fruit. The breakfast was very predictable. The location was great. It was right where we wanted to be, near the Stadium.Guest review byEdson L SanchesUnited States
- From US$56 per nightScored out of 10, guest rating 8.0Very good - What previous guests thought, 392 reviewsI liked all about this place. Very clean, quiet, modern, with all facilities! All I needed and expected to have, I had it at the reach of my hand. People were very nice and helped me with all questions I could have. I'd recommend this place to everyone!Guest review byJacekCanada
- From US$125.10 per nightScored out of 10, guest rating 8.8Fabulous - What previous guests thought, 485 reviewsThe room was was clean and comfortable. Pool was amazing. Spa and massage were lovely. Reception staff and restaurant staff very friendly. Food was good .Guest review byKatieIreland
- From US$120 per nightScored out of 10, guest rating 7.6Good - What previous guests thought, 539 reviewsFree airport shuttle. They were willing to wait for me at the airport while I had a Bolivian SIMM card put in my phone and had the phone registered.Guest review byHowardCanada
- From US$83.62 per nightScored out of 10, guest rating 7.8Good - What previous guests thought, 1,105 reviewsVery central. Comfortable and great value. Helpful staff. Great shower. Would recommend. Stayed twice.Guest review byMARKUnited Kingdom
- From US$69.90 per nightScored out of 10, guest rating 7.4Good - What previous guests thought, 178 reviewsGood value, comfortable, close to the plaza and helpful staff.Guest review byMichaelPeru
- From US$66.89 per nightScored out of 10, guest rating 8.0Very good - What previous guests thought, 391 reviewsLocation and faculties were fabulous and quite a trendy HotelGuest review bystuartUnited Kingdom
Planning a trip? Get inspired by reviews of cities in Santa Cruz Region
- 6.0
It's a city with not much to offer.
It's a city with not much to offer. You're better off in La Paz, where the views are nicer, the scenery is just better. But you're really much better off in the more rural places, in the mountains, by the lakes and away from the cities.Guest review byOgnyanUnited Kingdom - 8.0
Santa Cruz de la Sierra is an interesting city with a busy...
Santa Cruz de la Sierra is an interesting city with a busy and parcely old part downtown. You find museums, the main plaza with the cathedral, shops for everyone, big restaurants and small places who sell delicious local food. Also thera are some modern shopping malls as also black markets where you find everything you might need for living. Cultural events are offered and some really nice places with abundant semi-tropical vegetation as well as places with a lake to swim and hotels. You can take a taxi or go by bus to almost every place you like, in general it is very safe, only in the outskirts you should be more careful and maybe not go there at nigt. Always take your purse with important things in front of you - just in case! I certainly recommend Santa Cruz for a visit! A little bit outside there are the sanddunes and the botanical garden and other places like the Chiquitania, also very worth visiting!Guest review byCorneliaGermany - 8.0
Friendly people (is famous for its hospitality).
Friendly people (is famous for its hospitality). Is the most productive area of the country, you can find everything you expect of a big city. I like my staying and I will be back with more time and better organized agenda. Given the size of the city and the weather (mostly humid and hot) a car is necessary to visit properly Santa Cruz.Guest review byFlavio David Y.Bolivia